Caveolin-1 Gene Therapy Reduces TDP-43 Related Neurodegeneration in a Mouse Model
You might recall that gene therapy to overexpress caveolin-1 in the brain was recently shown to reduce pathology in a mouse model of Alzheimer's disease. In tod...
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The Brain Waste System Disrupted by Alzheimer’s Mapped
A new study uses fluorescent ZsGreen tracking to unmask the brain's
PM20D1 Creates N-oleoyl-Leucine to Improve Clearance of Amyloid-β Aggregates by Microglia
Researchers here note a mechanism that encourages the innate immune cells known as microglia to better clear amyloid-β in the aging brain. The protein PM20D1 a...