Mechanistic insights into the disaggregation of amyloid-β fibrils by EPPS via replica-exchange molecular dynamics simulations

Mechanistic insights into the disaggregation of amyloid-β fibrils by EPPS via replica-exchange molecular dynamics simulations

Summary

Amyloid-β (Aβ) fibrils are considered key pathological agents in the progression of Alzheimer’s disease. Recent studies demonstrated that N-(2-hydroxyethyl)...

Description

Amyloid-β (Aβ) fibrils are considered key pathological agents in the progression of Alzheimer’s disease. Recent studies demonstrated that N-(2-hydroxyethyl)...

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